Postdoctoral fellow (Molecular/cellular biology)

Lokalizacja Wrocław
Termin składania aplikacji 03.02.2022

Łukasiewicz Research Network – PORT Polish Center for Technology Development is a research institute within the Łukasiewicz Research Network. It focuses on development of new technologies, resulting from basic and applied research performed at the Institute in the area of biotechnology. These technologies, in turn, serve as a basis for innovative solutions for the industry. The Center is located on a historical campus of Pracze in Wroclaw in Southwestern Poland. It currently employs more than 250 scientists and support staff in four Centres: Biotechnology, Biomedicine (including state-of-the-art Biobank), Materials Science and Engineering and a well-equipped Core Facility.

Laboratory of Genome Dynamics (led by dr Michal Malewicz) located at the Life Science Biotechnology Center (LSnBC) focuses on in dissecting the mechanisms of cellular response to DNA damage (DDR). The position will involve studying the mechanisms of mammalian DNA damage inducible cell cycle checkpoints using state-of-the-art methods of molecular and cell biology. Project is financed through NCN OPUS grant and focuses on dissection of molecular mechanisms governing G2/M checkpoints induction in human cells and on how these checkpoint are dysregulated in lung cancers.

We currently seek applicants for

Postdoctoral fellow (Molecular/cellular biology)

Location: Wrocław, Poland

Ref. no. RE/PhD/MM/2022

Major responsibilities

  • Study the mechanisms underlying mammalian DNA damage response (DDR) including: with the primary focus on G2/M checkpoints.
  • Identification of novel drug targets and disease-specific pathways for DDR (strong focus will be placed on finding new synthetic lethality interactions in lung cancers).
  • Study the localization, interactions and function of proteins involved in DDR and associated diseases.
  • Perform genetic and pharmacological screens to identify compounds with novel drug potential.
  • Histological analysis of cancer tissue.

Qualifications

  • PhD title or equivalent (doctoral students in their final year will be considered).
  • Documented scientific achievements published in recognised international journals (candidates without first-authored papers will not be considered).
  • Experience in molecular biology laboratory work including ability to conduct well-designed experiments.
  • Experience in working with mammalian cell culture.
  • Good knowledge of molecular biology and cell biology including gene cloning and analysis of gene expression.
  • Experience in working with genome engineering tools such as CRISPR and/or Base editing.
  • Good command of English language.
  • Teamwork, great work organization and communication skills.
  • Experience in working in foreign laboratories will be considered as an additional advantage.

Our offer

  • Full time competitive contract of employment for the position of a Senior Specialist.
  • A friendly, inspiring, interdisciplinary environment.
  • Opportunity for personal and professional development.
  • We subsidies private medical care.

Please send your resume via link:

https://system.erecruiter.pl/FormTemplates/RecruitmentForm.aspx?WebID=66f46cfe518a467c827b8f1602d49a24

Application deadline: 03.02.2022

Please note that we will contact only selected candidates.