RESEARCH ENGINEER IN GENOME DYNAMICS RESEARCH GROUP
PORT is seeking
Research Engineer in Genome Dynamics Research Group
ref. no IB/DG/2021
Laboratory of Genome Dynamics (led by dr Michal Malewicz) focuses on in dissecting the mechanisms of cellular response to DNA damage (DDR). The position will involve studying the mechanisms of mammalian DNA repair and checkpoint induction using state-of-the-art methods of molecular and cell biology.
- Study the mechanisms underlying mammalian DNA damage response (DDR) including: DNA repair, checkpoints, composition of DDR protein complexes and their posttranslational modifications.
- Identification of novel drug targets and disease-specific pathways for DDR.
- Study the localization, interactions and function of proteins involved in DDR and associated diseases.
- Perform genetic and pharmacological screens to identify compounds with novel drug potential.
- PhD title or equivalent (doctoral students in their final year will be considered).
- Documented scientific achievements published in recognised international journals.
- Experience in laboratory work including ability to conduct well-designed experiments.
- Experience in working with mammalian cell culture (knowledge of iPS culture and differentiation methods as well as organoid derivation would be a distinct advantage).
- Good knowledge of molecular biology and cell biology including gene cloning and analysis of gene expression.
- Experience in working with genome engineering tools such as CRISPR and/or Base editing.
- Good command of English language.
- Teamwork, great work organization and communication skills.
- Experience in working in foreign laboratories will be considered as an additional advantage.
What we offer:
- Full time competitive contract on the position: Specialist
- A friendly, inspiring, interdisciplinary environment.
- Opportunity for personal and professional development.
Application deadline: 24th August, 2021
Please note that we will contact only selected candidates.